Búsqueda | Biblioteca Virtual en Salud Fronteriza

1.

Distinct transcriptome architectures underlying lupus establishment and exacerbation.

Nakano, Masahiro; Ota, Mineto; Takeshima, Yusuke; Iwasaki, Yukiko; Hatano, Hiroaki; Nagafuchi, Yasuo; Itamiya, Takahiro; Maeda, Junko; Yoshida, Ryochi; Yamada, Saeko; Nishiwaki, Aya; Takahashi, Haruka; Takahashi, Hideyuki; Akutsu, Yuko; Kusuda, Takeshi; Suetsugu, Hiroyuki; Liu, Lu; Kim, Kwangwoo; Yin, Xianyong; Bang, So-Young; Cui, Yong; Lee, Hye-Soon; Shoda, Hirofumi; Zhang, Xuejun; Bae, Sang-Cheol; Terao, Chikashi; Yamamoto, Kazuhiko; Okamura, Tomohisa; Ishigaki, Kazuyoshi; Fujio, Keishi.

Cell ; 185(18): 3375-3389.e21, 2022 09 01.

Artículo en Inglés | MEDLINE | ID: mdl-35998627

2.

Dynamic landscape of immune cell-specific gene regulation in immune-mediated diseases.

Ota, Mineto; Nagafuchi, Yasuo; Hatano, Hiroaki; Ishigaki, Kazuyoshi; Terao, Chikashi; Takeshima, Yusuke; Yanaoka, Haruyuki; Kobayashi, Satomi; Okubo, Mai; Shirai, Harumi; Sugimori, Yusuke; Maeda, Junko; Nakano, Masahiro; Yamada, Saeko; Yoshida, Ryochi; Tsuchiya, Haruka; Tsuchida, Yumi; Akizuki, Shuji; Yoshifuji, Hajime; Ohmura, Koichiro; Mimori, Tsuneyo; Yoshida, Ken; Kurosaka, Daitaro; Okada, Masato; Setoguchi, Keigo; Kaneko, Hiroshi; Ban, Nobuhiro; Yabuki, Nami; Matsuki, Kosuke; Mutoh, Hironori; Oyama, Sohei; Okazaki, Makoto; Tsunoda, Hiroyuki; Iwasaki, Yukiko; Sumitomo, Shuji; Shoda, Hirofumi; Kochi, Yuta; Okada, Yukinori; Yamamoto, Kazuhiko; Okamura, Tomohisa; Fujio, Keishi.

Cell ; 184(11): 3006-3021.e17, 2021 05 27.

Artículo en Inglés | MEDLINE | ID: mdl-33930287

3.

Immunomics analysis of rheumatoid arthritis identified precursor dendritic cells as a key cell subset of treatment resistance.

Yamada, Saeko; Nagafuchi, Yasuo; Wang, Min; Ota, Mineto; Hatano, Hiroaki; Takeshima, Yusuke; Okubo, Mai; Kobayashi, Satomi; Sugimori, Yusuke; Masahiro, Nakano; Yoshida, Ryochi; Hanata, Norio; Suwa, Yuichi; Tsuchida, Yumi; Iwasaki, Yukiko; Sumitomo, Shuji; Kubo, Kanae; Shimane, Kenichi; Setoguchi, Keigo; Azuma, Takanori; Kanda, Hiroko; Shoda, Hirofumi; Zhang, Xuan; Yamamoto, Kazuhiko; Ishigaki, Kazuyoshi; Okamura, Tomohisa; Fujio, Keishi.

Ann Rheum Dis ; 82(6): 809-819, 2023 06.

Artículo en Inglés | MEDLINE | ID: mdl-36918189

4.

Combined plasma metabolomic and transcriptomic analysis identify histidine as a biomarker and potential contributor in SLE pathogenesis.

Iwasaki, Yukiko; Takeshima, Yusuke; Nakano, Masahiro; Okubo, Mai; Ota, Mineto; Suzuki, Akari; Kochi, Yuta; Okamura, Tomohisa; Endo, Takaho; Miki, Ichiro; Sakurada, Kazuhiro; Yamamoto, Kazuhiko; Fujio, Keishi.

Rheumatology (Oxford) ; 62(2): 905-913, 2023 02 01.

Artículo en Inglés | MEDLINE | ID: mdl-35689621

5.

Immune cell multiomics analysis reveals contribution of oxidative phosphorylation to B-cell functions and organ damage of lupus.

Takeshima, Yusuke; Iwasaki, Yukiko; Nakano, Masahiro; Narushima, Yuta; Ota, Mineto; Nagafuchi, Yasuo; Sumitomo, Shuji; Okamura, Tomohisa; Elkon, Keith; Ishigaki, Kazuyoshi; Suzuki, Akari; Kochi, Yuta; Yamamoto, Kazuhiko; Fujio, Keishi.

Ann Rheum Dis ; 81(6): 845-853, 2022 06.

Artículo en Inglés | MEDLINE | ID: mdl-35236659

6.

Control of naive and effector CD4 T cell receptor repertoires by rheumatoid-arthritis-risk HLA alleles.

Nagafuchi, Yasuo; Ota, Mineto; Hatano, Hiroaki; Inoue, Mariko; Kobayashi, Satomi; Okubo, Mai; Sugimori, Yusuke; Nakano, Masahiro; Yamada, Saeko; Yoshida, Ryochi; Tsuchida, Yumi; Iwasaki, Yukiko; Shoda, Hirofumi; Okada, Yukinori; Yamamoto, Kazuhiko; Ishigaki, Kazuyoshi; Okamura, Tomohisa; Fujio, Keishi.

J Autoimmun ; 133: 102907, 2022 12.

Artículo en Inglés | MEDLINE | ID: mdl-36126366

7.

Dysregulation of the gene signature of effector regulatory T cells in the early phase of systemic sclerosis.

Kobayashi, Satomi; Nagafuchi, Yasuo; Okubo, Mai; Sugimori, Yusuke; Hatano, Hiroaki; Yamada, Saeko; Nakano, Masahiro; Yoshida, Ryochi; Takeshima, Yusuke; Ota, Mineto; Tsuchida, Yumi; Iwasaki, Yukiko; Setoguchi, Keigo; Kubo, Kanae; Okamura, Tomohisa; Yamamoto, Kazuhiko; Shoda, Hirofumi; Fujio, Keishi.

Rheumatology (Oxford) ; 61(10): 4163-4174, 2022 10 06.

Artículo en Inglés | MEDLINE | ID: mdl-35040949

8.

Branched chain amino acids in the treatment of polymyositis and dermatomyositis: a phase II/III, multi-centre, randomized controlled trial.

Kimura, Naoki; Kawahara, Takuya; Uemura, Yukari; Atsumi, Tatsuya; Sumida, Takayuki; Mimura, Toshihde; Kawaguchi, Yasushi; Amano, Hirofumi; Iwasaki, Yukiko; Kaneko, Yuko; Matsui, Toshihiro; Muro, Yoshinao; Imura, Yoshitaka; Kanda, Takashi; Tanaka, Yoshiya; Kawakami, Atsushi; Jinnin, Masatoshi; Ishii, Tomonori; Hiromura, Keiju; Miwa, Yusuke; Nakajima, Hiroshi; Kuwana, Masataka; Nishioka, Yasuhiko; Morinobu, Akio; Kameda, Hideto; Kohsaka, Hitoshi.

Rheumatology (Oxford) ; 61(11): 4445-4454, 2022 11 02.

Artículo en Inglés | MEDLINE | ID: mdl-35179548

9.

ANCA-associated vasculitis with protein-losing enteropathy is characterized by hypocomplementemia.

Goto, Manaka; Tsuchida, Yumi; Terada, Keigo; Takahashi, Hideyuki; Sugimori, Yusuke; Komai, Toshihiko; Iwasaki, Yukiko; Shoda, Hirofumi; Fujio, Keishi.

Rheumatol Int ; 42(10): 1863-1872, 2022 10.

Artículo en Inglés | MEDLINE | ID: mdl-34156527

10.

Integrated bulk and single-cell RNA-sequencing identified disease-relevant monocytes and a gene network module underlying systemic sclerosis.

Kobayashi, Satomi; Nagafuchi, Yasuo; Okubo, Mai; Sugimori, Yusuke; Shirai, Harumi; Hatano, Hiroaki; Junko, Maeda; Yanaoka, Haruyuki; Takeshima, Yusuke; Ota, Mineto; Iwasaki, Yukiko; Sumitomo, Shuji; Okamura, Tomohisa; Yamamoto, Kazuhiko; Shoda, Hirofumi; Fujio, Keishi.

J Autoimmun ; 116: 102547, 2021 01.

Artículo en Inglés | MEDLINE | ID: mdl-33039247

11.

Identifying the most influential gene expression profile in distinguishing ANCA-associated vasculitis from healthy controls.

Yanaoka, Haruyuki; Nagafuchi, Yasuo; Hanata, Norio; Takeshima, Yusuke; Ota, Mineto; Suwa, Yuichi; Shirai, Harumi; Sugimori, Yusuke; Okubo, Mai; Kobayashi, Satomi; Hatano, Hiroaki; Yamada, Saeko; Tsuchida, Yumi; Iwasaki, Yukiko; Sumitomo, Shuji; Shoda, Hirofumi; Okada, Masato; Okamura, Tomohisa; Yamamoto, Kazuhiko; Fujio, Keishi.

J Autoimmun ; 119: 102617, 2021 05.

Artículo en Inglés | MEDLINE | ID: mdl-33677398

12.

Egr2 and Egr3 in regulatory T cells cooperatively control systemic autoimmunity through Ltbp3-mediated TGF-ß3 production.

Morita, Kaoru; Okamura, Tomohisa; Inoue, Mariko; Komai, Toshihiko; Teruya, Shuzo; Iwasaki, Yukiko; Sumitomo, Shuji; Shoda, Hirofumi; Yamamoto, Kazuhiko; Fujio, Keishi.

Proc Natl Acad Sci U S A ; 113(50): E8131-E8140, 2016 12 13.

Artículo en Inglés | MEDLINE | ID: mdl-27911796

13.

Effect of Host Moieties on the Phosphorescent Spectrum of Green Platinum Complex.

Iwasaki, Yukiko; Fukagawa, Hirohiko; Shimizu, Takahisa.

Molecules ; 24(3)2019 Jan 28.

Artículo en Inglés | MEDLINE | ID: mdl-30696004

14.

Splicing variant of WDFY4 augments MDA5 signalling and the risk of clinically amyopathic dermatomyositis.

Kochi, Yuta; Kamatani, Yoichiro; Kondo, Yuya; Suzuki, Akari; Kawakami, Eiryo; Hiwa, Ryosuke; Momozawa, Yukihide; Fujimoto, Manabu; Jinnin, Masatoshi; Tanaka, Yoshiya; Kanda, Takashi; Cooper, Robert G; Chinoy, Hector; Rothwell, Simon; Lamb, Janine A; Vencovský, Jirí; Mann, Herman; Ohmura, Koichiro; Myouzen, Keiko; Ishigaki, Kazuyoshi; Nakashima, Ran; Hosono, Yuji; Tsuboi, Hiroto; Kawasumi, Hidenaga; Iwasaki, Yukiko; Kajiyama, Hiroshi; Horita, Tetsuya; Ogawa-Momohara, Mariko; Takamura, Akito; Tsunoda, Shinichiro; Shimizu, Jun; Fujio, Keishi; Amano, Hirofumi; Mimori, Akio; Kawakami, Atsushi; Umehara, Hisanori; Takeuchi, Tsutomu; Sano, Hajime; Muro, Yoshinao; Atsumi, Tatsuya; Mimura, Toshihide; Kawaguchi, Yasushi; Mimori, Tsuneyo; Takahashi, Atsushi; Kubo, Michiaki; Kohsaka, Hitoshi; Sumida, Takayuki; Yamamoto, Kazuhiko.

Ann Rheum Dis ; 77(4): 602-611, 2018 04.

Artículo en Inglés | MEDLINE | ID: mdl-29331962

15.

Polymorphic lymphoproliferative disorders in patients with rheumatoid arthritis are associated with a better clinical outcome.

Tsukui, Daisuke; Kanda, Hiroko; Shinozaki-Ushiku, Aya; Tateishi, Shoko; Takeshima, Yusuke; Nagafuchi, Yasuo; Sasaki, Oh; Iwasaki, Yukiko; Harada, Hiroaki; Shibuya, Mihoko; Sumitomo, Shuji; Shoda, Hirofumi; Kubo, Kanae; Fujio, Keishi; Nakamura, Fumihiko; Kurokawa, Mineo; Fukayama, Masashi; Yamamoto, Kazuhiko.

Mod Rheumatol ; 28(4): 621-625, 2018 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-29057700

16.

Efficacy of intensive immunosuppression in exacerbated rheumatoid arthritis-associated interstitial lung disease.

Ota, Mineto; Iwasaki, Yukiko; Harada, Hiroaki; Sasaki, Oh; Nagafuchi, Yasuo; Nakachi, Shinichiro; Sumitomo, Shuji; Shoda, Hirofumi; Tohma, Shigeto; Fujio, Keishi; Yamamoto, Kazuhiko.

Mod Rheumatol ; 27(1): 22-28, 2017 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-27142966

17.

Emerging roles of Egr2 and Egr3 in the control of systemic autoimmunity.

Morita, Kaoru; Okamura, Tomohisa; Sumitomo, Shuji; Iwasaki, Yukiko; Fujio, Keishi; Yamamoto, Kazuhiko.

Rheumatology (Oxford) ; 55(suppl 2): ii76-ii81, 2016 12.

Artículo en Inglés | MEDLINE | ID: mdl-27856665

18.

Lnk/Sh2b3 controls the production and function of dendritic cells and regulates the induction of IFN-Î³-producing T cells.

Mori, Taizo; Iwasaki, Yukiko; Seki, Yoichi; Iseki, Masanori; Katayama, Hiroko; Yamamoto, Kazuhiko; Takatsu, Kiyoshi; Takaki, Satoshi.

J Immunol ; 193(4): 1728-36, 2014 Aug 15.

Artículo en Inglés | MEDLINE | ID: mdl-25024389

19.

[Basic research overview in rheumatoid arthritis].

Iwasaki, Yukiko; Yamamoto, Kazuhiko.

Nihon Rinsho ; 74(6): 889-96, 2016 Jun.

Artículo en Japonés | MEDLINE | ID: mdl-27311174

20.

Lnk prevents inflammatory CD8âº T-cell proliferation and contributes to intestinal homeostasis.

Katayama, Hiroko; Mori, Taizo; Seki, Yoichi; Anraku, Masaki; Iseki, Masanori; Ikutani, Masashi; Iwasaki, Yukiko; Yoshida, Nobuaki; Takatsu, Kiyoshi; Takaki, Satoshi.

Eur J Immunol ; 44(6): 1622-32, 2014 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-24536025

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